Rabu, 07 September 2011

MORBUS HANSEN (1)

Gerhard Armauer Hansen



Born 29 July 1841(1841-07-29)
Bergen, Norway
Died 12 February 1912(1912-02-12) (aged 70)
Florø, Norway
Fields Epidemiology
Alma mater University of Oslo
Notable awards Royal Norwegian Order of St. Olav

Gerhard Henrik Armauer Hansen (29 July 1841 – 12 February 1912) was a Norwegian physician, remembered for his identification of the bacterium Mycobacterium leprae in 1873 as the causative agent of leprosy.

Hansen was born in Bergen and studied medicine at the Royal Frederik's University (now the University of Oslo), gaining his degree in 1866. He served a brief internship at the National Hospital in Christiania (Oslo) and as a doctor in Lofoten. In 1868 Hansen returned to Bergen to study leprosy while working with Daniel Cornelius Danielssen, a noted expert.

Leprosy was regarded as largely hereditary or otherwise miasmic in origin. Hansen concluded on the basis of epidemiological studies that leprosy was a specific disease with a specific cause. In 1870-71 Hansen travelled to Bonn and Vienna to gain the training necessary for him to prove his hypothesis. In 1873, he announced the discovery of Mycobacterium leprae in the tissues of all sufferers, although he did not identify them as bacteria, and received little support.

In 1879 he gave tissue samples to Albert Neisser who successfully stained the bacteria and announced his findings in 1880, claiming to have discovered the disease-causing organism. There was some conflict between Neisser and Hansen, Hansen as discoverer of the bacillus and Neisser as identifier of it as the etiological agent. Neisser put in some effort to downplay the assistance of Hansen. Hansen's claim was injured by his failure to produce a pure microbiological culture in an artificial medium or to prove that the rod-shaped organisms were infectious. Further Hansen had attempted to infect at least one female patient without consent and although no damage was caused, that case ended in court and Hansen lost his post at the hospital.

Hansen remained medical officer for leprosy in Norway and it was through his efforts that the leprosy acts of 1877 and 1885 were passed, leading to a steady decline of the disease in Norway from 1,800 known cases in 1875 to just 575 cases in 1901. His distinguished work was recognized at the International Leprosy Congress held at Bergen in 1909.

Hansen had suffered from syphilis since the 1860s but died of heart disease.

In Bergen, a medical museum has been designated Hansen, which is often referred to as the Leprosy Museum. The University of Bergen has also dedicated a research facility to him - Armauer Hansen Building - located at Haukeland University Hospital in Bergen. The Leprosy Archives in Bergen has been nominated by UNESCO to the list:Memory of the World.

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